Kinetics is designed for medical students preparing for Step 1, Step 2 CK, and Step 3, built around the 2026 USMLE update that broadened nutrition biochemistry and chronic-disease testing across all three Step exams. Every case, pathway, and question is mapped to the JAMA 2024 nutrition-competency framework that the USMLE cites as its alignment standard.
WHO IT'S FOR
‣ Medical students preparing for USMLE Step 1, Step 2 CK, and Step 3
‣ M1/M2 students in biochemistry and nutrition courses
‣ International medical graduates (IMGs) preparing for US licensure
‣ Residents reviewing nutrition for in-training exams or board recertification
‣ PA, NP, and pharmacy students mastering nutrition mechanisms
THE FOUR-PILLAR LOOP
Every session follows the same flow:
‣ QUESTION - Practice with NBME-format vignettes. Pick from five lettered choices. Get a mechanism-deep rationale for every answer - correct and distractor - plus a takeaway summary and JAMA competency tags.
‣ CASE - Open a patient vignette. Review the history. Order relevant labs at a cost - targeted workups earn more. Commit to a differential diagnosis.
‣ PATHWAY - Once you nail the DDx, map the biochemistry. Drag substrate, enzyme, cofactor, and product into a mechanism chain that explains why the clinical picture emerged. Understanding builds as you build.
‣ SPACED REPETITION - Missed a pathway? It returns tomorrow. Nailed it? It advances to 3, 7, or 21 days. Your knowledge stays durable between now and test day. Every question links to a relevant pathway and case for drill-deeper learning - wrong answers become entry points to mechanism mastery, not dead ends.
CONTENT
‣ 260+ NBME-format USMLE-style questions across Step 1, Step 2 CK, and Step 3, with full per-distractor rationales and clinical takeaways
‣ 22 topic anchors: 13 vitamins, 6 minerals, and 3 macronutrient pathways - carbohydrate, fatty-acid, and amino-acid metabolism (urea-cycle nitrogen disposal)
‣ 100+ clinical cases covering deficiency, toxicity, and dysregulation
‣ 70+ mechanism-chain pathways, each with a clinical pearl
‣ Drug-induced deficiencies taught as causal chains: metformin and B12 in long-term diabetics, phenytoin and folate in seizure patients, TMP-SMX and folate on PCP prophylaxis, and more. Includes a searchable drug-nutrient interaction index for fast lookup.
‣ Macronutrient metabolism aligned with current Step 2 emphasis: gluconeogenesis, insulin signaling, β-oxidation, ketogenesis, NAFLD/SREBP, urea-cycle hyperammonemia
‣ Lifespan-specific pathways: periconception folate, maternal iodine, infant B12, neonatal vitamin K, congenital cretinism
‣ Food allergy vs intolerance discrimination (cow's milk protein allergy, celiac disease)
‣ Eating-disorder identification with DSM-5 criteria and refeeding-syndrome management protocol
‣ Nutrition label interpretation for chronic-disease counseling
‣ A competency dashboard tracking your progress against every JAMA 2024 nutrition competency the app teaches
FREE TIER
Vitamin B12 unlocked forever. Six cases (pernicious anaemia, nitrous-oxide-induced SACD, infant of vegan mother, metformin in long-term diabetics, post-bariatric SACD, terminal ileal Crohn resection), four pathways (MMA cycle, breastmilk-infant myelination, metformin–B12 mechanism, PPI multi-nutrient malabsorption), and 17 questions - enough to run the complete question → case → pathway → review loop and decide if Kinetics fits your study style.
ONE-TIME PURCHASE
One-time purchase. No subscription. Every future content update included.
BUILT BY DIAGNOSTIC STUDIOS
Also makers of MedDiagnosis (clinical case simulator) and PathoPlay (disease and drug mechanisms).
For educational use only. Not for clinical decision-making.
USMLE® is a registered trademark of the FSMB and NBME. Kinetics is independent and not affiliated with or endorsed by the USMLE program, FSMB, or NBME.
Recent changes:
Focused USMLE nutrition prep for Step 1, Step 2 CK, and Step 3.
• Clinical cases that test applied nutrition reasoning
• Biochemistry pathways with interactive flow
• Spaced repetition tuned for exam prep
• Question bank for targeted review
Built around the June 2026 USMLE nutrition content expansion. One topic, covered thoroughly.
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