OpenEvidence is a clinical decision support and medical search engine designed for healthcare professionals. It sources and cites content from 300+ medical journals, FDA and CDC, with official partnerships including NEJM and JAMA, spanning NCCN, ACC, ADA, ACEP, AAFP and more. Trusted by hundreds of thousands of clinicians and used daily by over 40% of U.S. physicians across more than 10,000 hospitals, it delivers evidence-based answers at the point of care.
Pros & Cons
Large, professional user base (hundreds of thousands of clinicians)
High engagement among U.S. physicians (used daily by a substantial share of doctors)
Rich, up-to-date content from 300+ journals plus FDA/CDC sources
Strong credibility through NEJM/JAMA partnerships and a broad network of medical organizations
Content and features focused on clinicians; may lack patient-facing content found in some consumer medical apps
Some competitors emphasize CME, patient education, or broader ‘guidelines’ tools not described here
Potential visitors should verify professional status due to HCP-only access model
About OpenEvidence
OpenEvidence is a medical app developed by OpenEvidence.
How many times has OpenEvidence been downloaded?
OpenEvidence has been downloaded 500 thousand times. In the last 30 days, the app was downloaded 24 thousand times. It is ranked in the top 100 medical apps.
What is the rating of OpenEvidence?
OpenEvidence is rated 4.85 out of 5 stars, based on 4.3 thousand ratings.
Is OpenEvidence free?
OpenEvidence is free to download. The APK download size is 120.11 MB. The latest version available is 2.9.24. The last update was on August 11, 2026.
What are the requirements for OpenEvidence?
The app has a content rating of Everyone. The app has been available on Google Play October 2024.
Description
Clinical Decision Support & Medical Search Engine for Healthcare Professionals (NPI Required).
OpenEvidence is trusted by hundreds of thousands of verified healthcare professionals to support high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature.
OpenEvidence is the fastest-growing and most widely-used clinical decision support platform in the world–used daily, on average, by over 40% of physicians in the United States, spanning more than 10,000 hospitals and medical centers nationwide.
Now sourcing from over 300+ medical journals, as well as the FDA and CDC. OpenEvidence is an official AI partner of The New England Journal of Medicine and the Journal of American Medical Association (and their 11 specialty journals), and has content agreements, partnerships and collaborations with: • NCCN • ACC • ADA • ACEP • AAFP • AAOS • AAOHNS and more.
OpenEvidence is only available for health care professionals. Users must verify their health care professional status before using OpenEvidence.
TESTIMONIALS
“I've been using OpenEvidence for the last week - it has been amazing! Able to narrow down on results quickly and find information that I wasn't able to do with Google/PubMed searches on my own.” - Dr. John Lee, MD. Physician & Faculty Member, Harvard Medical School
“OpenEvidence can be the foundational technology to power all clinical decision tools.” - Dr. Antonio Jorge Forte, MD. Director of MayoExpert, Mayo Clinic
“OpenEvidence is more up-to-date than UpToDate. And more useful regardless, since it’s interactive, and you can ask it questions, and get very specific answers about specific medical fact patterns in a patient case. It’s like having a curbside consult with a team of expert physicians, but that you can carry around with you in your pocket.” - Dr. Ram Dandillaya, MD. Clinical Chief, Department of Cardiology, Cedars-Sinai Medical Center
“I am in community practice and medical director of a community cancer center. OpenEvidence has been an incredible lifeline for daily practitioners.” - C.J., Oncologist
“OpenEvidence is absolutely fantastic. I use it a gazillion times a day.” - J.A., Neurologist
“OpenEvidence’s efforts to make medicine more evidence-based are invaluable. The shift from judgment to calculation can reduce the level of noise currently found in medicine.” - Daniel Kahneman, Nobel Prize Laureate (In Memoriam)
“It is light years ahead of the next best medical oriented AI I have used.” - R.E.., Oncologist
Recent changes: * NEJM, JAMA, Nature, and NCCN content partnership * OE Education Platform - Earn CE and MOC credits from a personalized dashboard * EvidenceGrade™ - See the strength of evidence used in an OpenEvidence answer
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Excellent application that has easy to comprehend medical information and excellent up-to-date guidance for a busy family doctor.
★★★★★A Google user· Jun 2, 2026
Excellent source of quick, thorough evidence-based answers to clinical questions with applicable charts and algorithms as well as useful resources.
★★★★★Samantha Drew· Mar 1, 2026
Wonderful resource, quick answers, no extra fluff, easy to follow, with evidence based resources. What's not to love
★★★★★AP Gabai· Jun 24, 2026
Significantly more valuable than other AIs for healthcare pros. Great resources and links as well as actionable steps.
★☆☆☆☆Munish T· Mar 30, 2026
Had given evidence that would have let a patient die, and it was a pretty basic ICU patient. LLMs can not be trusted, and yet they are being relied upon as if it was a reliable resource
★☆☆☆☆Rob K· Jun 3, 2026
What about someone who is a NON-US HCP and doesn't possess a NPI? Make it accessible to the world not just to an area. Knowledge should be shared not reserved. Worst app.
★☆☆☆☆Stacy K· Jun 25, 2026
Can only access if you have an NPI#. As a radiologic technologist (a licensed healthcare professional), it's very disappointing that I don't have access to this app. All licensed healthcare professionals should have access to this app.
★★☆☆☆Mario Stoll· Feb 15, 2026
Great service. The low rating is only for the app: it keeps shutting down upon login (pixel 9 pro, android 16 Feb security update, November Google play update)
★★☆☆☆Christopher Bauer· Jul 16, 2026
Crashes repeatedly when trying to sign in on app. Can sign in on web without a problem.
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OpenEvidence is requesting 45 permissions and we don't have library information (yet).
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Trust & Safety: The app requests a broad set of permissions (location, camera, microphone, contacts, storage, notifications, etc.) to support interactive decision support and real-time search features. Access is restricted to verified healthcare professionals, aligning safety and trust expectations with its professional focus.
Each subscription will automatically renew 3 days before the expiration date for
the same time period. Subscriptions can be cancelled at any time before the renewal.
